HitPredict

Interactor 1: AT8B1 (O43520)
Phospholipid-transporting ATPase IC (EC 7.6.2.1) (ATPase class I type 8B member 1) (Familial intrahepatic cholestasis type 1) (P4-ATPase flippase complex alpha subunit ATP8B1)
Gene: ATP8B1

Interactor 2: CC50A (Q9NV96)
Cell cycle control protein 50A (P4-ATPase flippase complex beta subunit TMEM30A) (Transmembrane protein 30A)
Gene: TMEM30A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 1.00 0.887

The method score is based on:

Property Details
Experiments 21914794, 19731236, 20947505, 25947375
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CDC50~E1-E2_ATPase, CDC50~PhoLip_ATPase_C, CDC50~PhoLip_ATPase_N
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0005794 - Golgi apparatus
GO:0005886 - plasma membrane
GO:0006855 - xenobiotic transmembrane transport
GO:0016324 - apical plasma membrane
and 2 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

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Hs

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Last updated: 15 Jul 2024