Interactor 1: B2L11 (O43521)
Bcl-2-like protein 11 (Bcl2-L-11) (Bcl2-interacting mediator of cell death)
Gene: BCL2L11

Interactor 2: BAX (Q07812)
Apoptosis regulator BAX (Bcl-2-like protein 4) (Bcl2-L-4)
Gene: BAX

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.962

The method score is based on:

Property Details
Experiments 26186194, 18948948, 23235460, 17289999, 23374347, 19427863, 17525735
Identification Methods affinity chromatography technology, nuclear magnetic resonance, molecular sieving, surface plasmon resonance, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Bcl-2~Bclx_interact
Common GO terms GO:0001782 - B cell homeostasis
GO:0001822 - kidney development
GO:0002262 - myeloid cell homeostasis
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
and 17 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 198
Hs

1 192
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Rn
+ Mm
+ Rn
+ Mm
+ Rn
+ Hs
+ Rn
+ Mm
+ Rn

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024