Interactor 1: B2L11 (O43521)
Bcl-2-like protein 11 (Bcl2-L-11) (Bcl2-interacting mediator of cell death)
Gene: BCL2L11

Interactor 2: B2CL2 (Q92843)
Bcl-2-like protein 2 (Bcl2-L-2) (Apoptosis regulator Bcl-W)
Gene: BCL2L2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.976

The method score is based on:

Property Details
Experiments 16697956, 28514442, 9731710, 32296183, 33961781, 9430630, unassigned1304, 21199865, 17289999, 15694340
Identification Methods unspecified method, affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array, fluorescence polarization spectroscopy, validated two hybrid, surface plasmon resonance
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Bcl-2~Bclx_interact
Common GO terms GO:0005741 - mitochondrial outer membrane
GO:0005829 - cytosol
GO:0007283 - spermatogenesis
GO:0008630 - intrinsic apoptotic signaling pathway in response to DNA damage
GO:0042981 - regulation of apoptotic process
and 2 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 198
Hs

1 193
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Last updated: 15 Jul 2024