Interactor 1: B2L11 (O43521)
Bcl-2-like protein 11 (Bcl2-L-11) (Bcl2-interacting mediator of cell death)
Gene: BCL2L11
Interactor 2: B2CL2 (Q92843)
Bcl-2-like protein 2 (Bcl2-L-2) (Apoptosis regulator Bcl-W)
Gene: BCL2L2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 1.00 | 0.976 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 16697956, 28514442, 9731710, 32296183, 33961781, 9430630, unassigned1304, 21199865, 17289999, 15694340 |
| Identification Methods | unspecified method, affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array, fluorescence polarization spectroscopy, validated two hybrid, surface plasmon resonance |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Bcl-2~Bclx_interact |
| Common GO terms | GO:0005741 - mitochondrial outer membrane GO:0005829 - cytosol GO:0007283 - spermatogenesis GO:0008630 - intrinsic apoptotic signaling pathway in response to DNA damage GO:0042981 - regulation of apoptotic process and 2 others more... |
| Homologous interactions | 17 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
