Interactor 1: B2L11 (O43521)
Bcl-2-like protein 11 (Bcl2-L-11) (Bcl2-interacting mediator of cell death)
Gene: BCL2L11

Interactor 2: B2L10 (Q9HD36)
Bcl-2-like protein 10 (Bcl2-L-10) (Anti-apoptotic protein Boo) (Anti-apoptotic protein NrH) (Apoptosis regulator Bcl-B)
Gene: BCL2L10

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 0.90 0.870

The method score is based on:

Property Details
Experiments 32296183, 33961781, 23235460, unassigned1304
Identification Methods two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, surface plasmon resonance, validated two hybrid, x-ray crystallography, molecular sieving, dynamic light scattering, circular dichroism, two hybrid array and 1 others

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Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Bcl-2~Bclx_interact
Common GO terms GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
GO:0005829 - cytosol
GO:0006915 - apoptotic process
GO:0006919 - activation of cysteine-type endopeptidase activity involved in apoptotic process
and 3 others

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Homologous interactions 0

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Last updated: 15 Jul 2024