Interactor 1: FOXO3 (O43524)
Forkhead box protein O3 (AF6q21 protein) (Forkhead in rhabdomyosarcoma-like 1)
Gene: FOXO3

Interactor 2: CHK2 (O96017)
Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2)
Gene: CHEK2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 22893124
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0019901 - protein kinase binding
GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 673
Hs

1 543
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Dm
+ Dm
+ Hs
+ Ce
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024