Interactor 1: SMAD6 (O43541)
Mothers against decapentaplegic homolog 6 (MAD homolog 6) (Mothers against DPP homolog 6) (SMAD family member 6) (SMAD 6) (Smad6) (hSMAD6)
Gene: SMAD6

Interactor 2: FKB1A (P62942)
Peptidyl-prolyl cis-trans isomerase FKBP1A (PPIase FKBP1A) (EC 5.2.1.8) (12 kDa FK506-binding protein) (12 kDa FKBP) (FKBP-12) (Calstabin-1) (FK506-binding protein 1A) (FKBP-1A) (Immunophilin FKBP12) (Rotamase)
Gene: FKBP1A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.34 0.60 0.457

The method score is based on:

Property Details
Experiments 16720724
Identification Methods two hybrid
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0030512 - negative regulation of transforming growth factor beta receptor signaling pathway
GO:0032926 - negative regulation of activin receptor signaling pathway
GO:0034713 - type I transforming growth factor beta receptor binding
and 1 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 496
Hs

1 108
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024