Interactor 1: SMAD6 (O43541)
Mothers against decapentaplegic homolog 6 (MAD homolog 6) (Mothers against DPP homolog 6) (SMAD family member 6) (SMAD 6) (Smad6) (hSMAD6)
Gene: SMAD6

Interactor 2: SMAD4 (Q13485)
Mothers against decapentaplegic homolog 4 (MAD homolog 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4) (SMAD family member 4) (SMAD 4) (Smad4) (hSMAD4)
Gene: SMAD4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 9256479, 15817471
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains MH1~MH1, MH2~MH2
Common GO terms GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0003148 - outflow tract septum morphogenesis
GO:0003682 - chromatin binding
GO:0005634 - nucleus
and 15 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 496
Hs

1 552
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024