Interactor 1: XRCC3 (O43542)
DNA repair protein XRCC3 (X-ray repair cross-complementing protein 3)
Gene: XRCC3

Interactor 2: RAD51 (Q06609)
DNA repair protein RAD51 homolog 1 (HsRAD51) (hRAD51) (RAD51 homolog A)
Gene: RAD51

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.79 1.00 0.893

The method score is based on:

Property Details
Experiments 17302439, 28864920, 9660962, 11842113
Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains HHH_5~Rad51, Rad51~Rad51
Common GO terms GO:0000722 - telomere maintenance via recombination
GO:0000724 - double-strand break repair via homologous recombination
GO:0000781 - chromosome, telomeric region
GO:0005524 - ATP binding
GO:0005634 - nucleus
and 10 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 346
Hs

1 339
+ Hs
+ Cl
+ Sp
+ At
+ Hs
+ Ce
+ Hs
+ Sc
+ At
+ At
+ Sp
+ Sc
+ Hs
+ Hs
+ Hs
+ Sp
+ Hs
+ Sc

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Last updated: 15 Jul 2024