HitPredict

Interactor 1: XRCC2 (O43543)
DNA repair protein XRCC2 (X-ray repair cross-complementing protein 2)
Gene: XRCC2

Interactor 2: RA51D (O75771)
DNA repair protein RAD51 homolog 4 (R51H3) (RAD51 homolog D) (RAD51-like protein 3) (TRAD)
Gene: RAD51D

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 1.00 0.993

The method score is based on:

Property Details
Experiments 26186194, 27161866, 10749867, 28514442, 16717288, 11834724, 11751635, 10871607, 20189471, 30836272, 33961781, 25416956, 25910212, 12975363, 15115758, 32296183, 11842113, 34591612, 28864920, 31515488 and 2 others

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Identification Methods affinity chromatography technology, two hybrid, biochemical, pull down, far western blotting, molecular sieving, electron microscopy, two hybrid prey pooling approach, two hybrid array, validated two hybrid and 4 others

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Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Rad51~Rad51
Common GO terms GO:0000400 - four-way junction DNA binding
GO:0000724 - double-strand break repair via homologous recombination
GO:0005524 - ATP binding
GO:0005654 - nucleoplasm
GO:0005657 - replication fork
and 6 others

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Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 280
Hs

1 328
+ Hs
+ Mm
+ Hs
+ Cl
+ Sp
+ At
+ At
+ Hs
+ Hs
+ Hs
+ Dm
+ At
+ Ce
+ Ce
+ Hs
+ Hs
+ Hs
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024