Interactor 1: LAT (O43561)
Linker for activation of T-cells family member 1 (36 kDa phosphotyrosine adapter protein) (pp36) (p36-38)
Gene: LAT

Interactor 2: CD3G (P09693)
T-cell surface glycoprotein CD3 gamma chain (T-cell receptor T3 gamma chain) (CD antigen CD3g)
Gene: CD3G

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.61 0.55 0.580

The method score is based on:

Property Details
Experiments 32296183, unassigned1304
Identification Methods two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002250 - adaptive immune response
GO:0005886 - plasma membrane
GO:0030159 - signaling receptor complex adaptor activity
GO:0042110 - T cell activation
GO:0050852 - T cell receptor signaling pathway
Homologous interactions 0

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Last updated: 15 Jul 2024