Interactor 1: MCES (O43148)
mRNA cap guanine-N(7) methyltransferase (EC 2.1.1.56) (RG7MT1) (mRNA (guanine-N(7))-methyltransferase) (mRNA cap methyltransferase) (hCMT1) (hMet) (hcm1p)
Gene: RNMT
Interactor 2: RAMAC (Q9BTL3)
RNA guanine-N7 methyltransferase activating subunit (Protein FAM103A1) (RNA guanine-7 methyltransferase activating subunit) (RNMT-activating mRNA cap methyltransferase subunit) (RNMT-activating mini protein) (RAM)
Gene: RAMAC
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.89 | 0.90 | 0.898 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28514442, 32296183, 30021884, 33961781, unassigned1304, unassigned3799 |
| Identification Methods | affinity chromatography technology, two hybrid, proximity labelling technology, two hybrid array, two hybrid prey pooling approach, anti tag coimmunoprecipitation, cross-linking study, validated two hybrid |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | RAM~mRNA_G-N7_MeTrfase |
| Common GO terms | GO:0003723 - RNA binding GO:0005634 - nucleus GO:0006370 - 7-methylguanosine mRNA capping GO:0031533 - mRNA capping enzyme complex GO:0160130 - mRNA cap methyltransferase RNMT:RAMAC complex |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 11Aug2025
