HitPredict

Interactor 1: SPY2 (O43597)
Protein sprouty homolog 2 (Spry-2)
Gene: SPRY2

Interactor 2: SPY1 (O43609)
Protein sprouty homolog 1 (Spry-1)
Gene: SPRY1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.66 0.60 0.631

The method score is based on:

Property Details
Experiments 25416956, 15004239
Identification Methods two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000132 - establishment of mitotic spindle orientation
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0008285 - negative regulation of cell population proliferation
GO:0010719 - negative regulation of epithelial to mesenchymal transition
and 9 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 315
Hs

1 319
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024