Interactor 1: SPY2 (O43597)
Protein sprouty homolog 2 (Spry-2)
Gene: SPRY2
Interactor 2: RASH (P01112)
GTPase HRas (EC 3.6.5.2) (H-Ras-1) (Ha-Ras) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed]
Gene: HRAS
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 0.60 | 0.479 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 18048363 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0008285 - negative regulation of cell population proliferation GO:0030335 - positive regulation of cell migration GO:0070374 - positive regulation of ERK1 and ERK2 cascade |
| Homologous interactions | 8 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
