Interactor 1: SPY2 (O43597)
Protein sprouty homolog 2 (Spry-2)
Gene: SPRY2
Interactor 2: GRN (P28799)
Progranulin (PGRN) (Acrogranin) (Epithelin precursor) (Glycoprotein of 88 Kda) (GP88) (Glycoprotein 88) (Granulin precursor) (PC cell-derived growth factor) (PCDGF) (Proepithelin) (PEPI) [Cleaved into: Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Epithelin-2) (Granulin B); Granulin-4 (Epithelin-1) (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)]
Gene: GRN
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.54 | 0.60 | 0.573 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25910212 |
| Identification Methods | two hybrid, two hybrid bait and prey pooling approach, two hybrid array, validated two hybrid |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005886 - plasma membrane GO:0016020 - membrane GO:0030335 - positive regulation of cell migration |
| Homologous interactions | 4 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
