HitPredict

Interactor 1: SPY2 (O43597)
Protein sprouty homolog 2 (Spry-2)
Gene: SPRY2

Interactor 2: HXA1 (P49639)
Homeobox protein Hox-A1 (Homeobox protein Hox-1F)
Gene: HOXA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	32296183
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0007605 - sensory perception of sound
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 315 Hs			1 335
+	Hs
		829924 Q7Z783_HUMAN (1-312): 9.45e-138: 395: 98.72		HXA1_HUMAN (1-302): 1.66e-60: 198: 100.00
+	Hs
		208329 SPY1_HUMAN (1-315): 1.06e-110: 325: 51.67		HXA1_HUMAN (1-302): 1.66e-60: 198: 100.00
+	Hs
		838087 Q7Z783_HUMAN (1-312): 9.45e-138: 395: 98.72		MEOX2_HUMAN (54-335): 1.36e-31: 122: 20.33
+	Hs
		208107 SPY2_HUMAN (1-315): 1.24e-136: 391: 100.00		MEOX2_HUMAN (54-335): 1.36e-31: 122: 20.33
+	Hs
		830014 SPY4_HUMAN (4-305): 6.69e-92: 277: 40.78		HXA1_HUMAN (1-302): 1.66e-60: 198: 100.00
+	Hs
		208413 SPY3_HUMAN (39-305): 3.2e-89: 269: 44.89		HXA1_HUMAN (1-302): 1.66e-60: 198: 100.00
+	Hs
		208331 SPY1_HUMAN (1-315): 1.06e-110: 325: 51.67		MEOX2_HUMAN (54-335): 1.36e-31: 122: 20.33
+	Hs
		208375 SPY1_HUMAN (1-315): 1.06e-110: 325: 51.67		Q6FHY5_HUMAN (54-335): 8.47e-32: 122: 19.67
+	Hs
		208414 SPY3_HUMAN (39-305): 3.2e-89: 269: 44.89		MEOX2_HUMAN (54-335): 1.36e-31: 122: 20.33
+	Hs
		208426 SPY3_HUMAN (39-305): 3.2e-89: 269: 44.89		Q6FHY5_HUMAN (54-335): 8.47e-32: 122: 19.67
+	Hs
		829922 SPRE1_HUMAN (142-277): 3.35e-39: 145: 25.18		HXA1_HUMAN (1-302): 1.66e-60: 198: 100.00
+	Hs
		446904 SPRE1_HUMAN (142-277): 3.35e-39: 145: 25.18		HXC4_HUMAN (142-328): 1.95e-36: 133: 32.09
+	Hs
		1151093 SPRE1_HUMAN (142-277): 3.35e-39: 145: 25.18		Q6FHY5_HUMAN (54-335): 8.47e-32: 122: 19.67
+	Hs
		838086 SPRE1_HUMAN (142-277): 3.35e-39: 145: 25.18		MEOX2_HUMAN (54-335): 1.36e-31: 122: 20.33
+	Hs
		453057 SPRE1_HUMAN (142-277): 3.35e-39: 145: 25.18		HXB7_HUMAN (86-298): 3.66e-32: 121: 24.20
+	Hs
		837817 SPRE1_HUMAN (142-277): 3.35e-39: 145: 25.18		MEOX1_HUMAN (42-312): 2.44e-30: 117: 22.88