HitPredict

Interactor 1: SPY2 (O43597)
Protein sprouty homolog 2 (Spry-2)
Gene: SPRY2

Interactor 2: CTSR1 (Q8NEC5)
Cation channel sperm-associated protein 1 (CatSper1) (hCatSper)
Gene: CATSPER1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	25416956, 32296183
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 315 Hs			1 780
+	Hs
		1192444 Q7Z783_HUMAN (1-312): 9.45e-138: 395: 98.72		CTSR1_HUMAN (1-780): 8.64e-140: 432: 100.00
+	Hs
		208429 SPY3_HUMAN (39-305): 3.2e-89: 269: 44.89		CTSR1_HUMAN (1-780): 8.64e-140: 432: 100.00
+	Hs
		1047251 SPY4_HUMAN (4-305): 6.69e-92: 277: 40.78		CAC1C_HUMAN (333-772): 3.69e-33: 140: 14.54
+	Hs
		132271 SPY1_HUMAN (1-315): 1.06e-110: 325: 51.67		CAC1A_HUMAN (51-360): 2.66e-10: 66.6: 12.65