HitPredict

Interactor 1: SPY2 (O43597)
Protein sprouty homolog 2 (Spry-2)
Gene: SPRY2

Interactor 2: KRA47 (Q9BYR0)
Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7)
Gene: KRTAP4-7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	25416956
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 315 Hs			1 155
+	Hs
		208189 SPY2_HUMAN (1-315): 1.24e-136: 391: 100.00		KRA92_HUMAN (1-150): 5.95e-29: 105: 42.00
+	Hs
		208183 SPY2_HUMAN (1-315): 1.24e-136: 391: 100.00		KR412_HUMAN (3-155): 4.54e-27: 102: 61.96
+	Hs
		208190 SPY2_HUMAN (1-315): 1.24e-136: 391: 100.00		KR411_HUMAN (1-125): 1.96e-18: 79.4: 54.40
+	Hs
		208122 SPY2_HUMAN (1-315): 1.24e-136: 391: 100.00		KR109_HUMAN (5-145): 5.14e-17: 77.4: 35.62
+	Hs
		208121 SPY2_HUMAN (1-315): 1.24e-136: 391: 100.00		KR108_HUMAN (1-124): 7.85e-17: 76.7: 35.66
+	Hs
		208123 SPY2_HUMAN (1-315): 1.24e-136: 391: 100.00		KR10B_HUMAN (4-154): 6.27e-15: 71.6: 25.29
+	Hs
		208120 SPY2_HUMAN (1-315): 1.24e-136: 391: 100.00		KR105_HUMAN (3-134): 7.89e-15: 71.3: 30.82
+	Hs
		208119 SPY2_HUMAN (1-315): 1.24e-136: 391: 100.00		KR103_HUMAN (45-155): 2.04e-13: 66.6: 36.04
+	Hs
		208118 SPY2_HUMAN (1-315): 1.24e-136: 391: 100.00		KR101_HUMAN (32-144): 5.59e-11: 60.9: 31.86
+	Hs
		208188 SPY2_HUMAN (1-315): 1.24e-136: 391: 100.00		KRA94_HUMAN (1-90): 1.8e-09: 55.1: 47.78
+	Hs
		208339 SPY1_HUMAN (1-315): 1.06e-110: 325: 51.67		KR122_HUMAN (16-155): 5.7e-27: 100: 34.75
+	Hs
		208346 SPY1_HUMAN (1-315): 1.06e-110: 325: 51.67		KR109_HUMAN (5-145): 5.14e-17: 77.4: 35.62
+	Hs
		208345 SPY1_HUMAN (1-315): 1.06e-110: 325: 51.67		KR108_HUMAN (1-124): 7.85e-17: 76.7: 35.66
+	Hs
		208347 SPY1_HUMAN (1-315): 1.06e-110: 325: 51.67		KR10B_HUMAN (4-154): 6.27e-15: 71.6: 25.29
+	Hs
		208343 SPY1_HUMAN (1-315): 1.06e-110: 325: 51.67		KR105_HUMAN (3-134): 7.89e-15: 71.3: 30.82
+	Hs
		208342 SPY1_HUMAN (1-315): 1.06e-110: 325: 51.67		KR103_HUMAN (45-155): 2.04e-13: 66.6: 36.04
+	Hs
		208341 SPY1_HUMAN (1-315): 1.06e-110: 325: 51.67		KR101_HUMAN (32-144): 5.59e-11: 60.9: 31.86
+	Hs
		208352 SPY1_HUMAN (1-315): 1.06e-110: 325: 51.67		KRA11_HUMAN (63-155): 2.35e-11: 60.5: 37.23
+	Hs
		208340 SPY1_HUMAN (1-315): 1.06e-110: 325: 51.67		KR123_HUMAN (67-155): 3.45e-11: 58.2: 34.44
+	Hs
		208344 SPY1_HUMAN (1-315): 1.06e-110: 325: 51.67		KR107_HUMAN (1-95): 1.04e-09: 57.4: 34.02