Interactor 1: SPY2 (O43597)
Protein sprouty homolog 2 (Spry-2)
Gene: SPRY2

Interactor 2: SPY4 (Q9C004)
Protein sprouty homolog 4 (Spry-4)
Gene: SPRY4

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.584

The method score is based on:

Property Details
Experiments 15004239, 16339969
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0032587 - ruffle membrane
GO:0040037 - negative regulation of fibroblast growth factor receptor signaling pathway
GO:0046580 - negative regulation of Ras protein signal transduction
GO:0048513 - animal organ development
and 1 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 315
Hs

1 299
+ Mm
+ Hs
+ Hs
+ Mm
+ Mm
+ Hs
+ Mm
+ Mm
+ Hs
+ Mm
+ Mm
+ Hs
+ Mm
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024