HitPredict

Interactor 1: DCX (O43602)
Neuronal migration protein doublecortin (Doublin) (Lissencephalin-X) (Lis-X)
Gene: DCX

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35063084
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005874 - microtubule GO:0008017 - microtubule binding GO:0019901 - protein kinase binding GO:0043005 - neuron projection
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 365 Hs			1 758
+	Hs
		166531 DCLK1_HUMAN (2-347): 5.53e-146: 432: 72.41		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		497299 DCLK2_HUMAN (2-349): 2.96e-144: 428: 67.49		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Mm
		498146 DCLK1_MOUSE (2-347): 4.65e-148: 438: 72.41		TAU_MOUSE (1-758): 1.4e-69: 244: 70.17
+	Mm
		498062 DCLK2_MOUSE (2-349): 8.21e-141: 419: 66.39		TAU_MOUSE (1-758): 1.4e-69: 244: 70.17
+	Hs
		208243 DCX_HUMAN (1-365): 0: 509: 100.00		MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56