HitPredict

Interactor 1: SPY1 (O43609)
Protein sprouty homolog 1 (Spry-1)
Gene: SPRY1

Interactor 2: MEOX2 (P50222)
Homeobox protein MOX-2 (Growth arrest-specific homeobox) (Mesenchyme homeobox 2)
Gene: MEOX2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	25416956, 32296183, 31515488
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 319 Hs			1 304
+	Hs
		208375 SPY1_HUMAN (1-319): 4.3e-127: 367: 100.00		Q6FHY5_HUMAN (1-304): 1.09e-56: 186: 98.36
+	Hs
		838087 Q7Z783_HUMAN (1-313): 1.06e-108: 321: 52.32		MEOX2_HUMAN (1-304): 2.38e-58: 190: 100.00
+	Hs
		208107 SPY2_HUMAN (1-319): 1.92e-107: 317: 52.28		MEOX2_HUMAN (1-304): 2.38e-58: 190: 100.00
+	Hs
		208414 SPY3_HUMAN (38-317): 1.7e-78: 242: 39.66		MEOX2_HUMAN (1-304): 2.38e-58: 190: 100.00
+	Hs
		208426 SPY3_HUMAN (38-317): 1.7e-78: 242: 39.66		Q6FHY5_HUMAN (1-304): 1.09e-56: 186: 98.36
+	Hs
		838086 SPRE1_HUMAN (63-281): 9.66e-62: 204: 21.15		MEOX2_HUMAN (1-304): 2.38e-58: 190: 100.00
+	Hs
		1151093 SPRE1_HUMAN (63-281): 9.66e-62: 204: 21.15		Q6FHY5_HUMAN (1-304): 1.09e-56: 186: 98.36
+	Hs
		453057 SPRE1_HUMAN (63-281): 9.66e-62: 204: 21.15		HXB7_HUMAN (69-256): 1.01e-34: 127: 29.02
+	Hs
		837817 SPRE1_HUMAN (63-281): 9.66e-62: 204: 21.15		MEOX1_HUMAN (4-270): 1.53e-28: 111: 36.73
+	Hs
		446904 SPRE1_HUMAN (63-281): 9.66e-62: 204: 21.15		HXC4_HUMAN (186-244): 1.32e-13: 71.2: 61.02