HitPredict

Interactor 1: FOXS1 (O43638)
Forkhead box protein S1 (Forkhead-like 18 protein) (Forkhead-related transcription factor 10) (FREAC-10)
Gene: FOXS1

Interactor 2: SMCA5 (O60264)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A5) (EC 3.6.4.-) (Sucrose nonfermenting protein 2 homolog) (hSNF2H)
Gene: SMARCA5

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	25609649
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 330 Hs			1 1052
+	Hs
		229367 FOXK2_HUMAN (2-324): 2.45e-54: 190: 22.42		SMCA5_HUMAN (19-1052): 0: 1097: 100.00
+	Hs
		229475 FOXB1_HUMAN (6-323): 1.84e-54: 182: 32.30		SMCA5_HUMAN (19-1052): 0: 1097: 100.00
+	Hs
		229346 FOXG1_HUMAN (16-302): 2.94e-52: 181: 30.00		SMCA5_HUMAN (19-1052): 0: 1097: 100.00
+	Hs
		229476 FOXC2_HUMAN (11-287): 3.91e-49: 173: 35.58		SMCA5_HUMAN (19-1052): 0: 1097: 100.00
+	Hs
		229380 FOXC1_HUMAN (5-181): 1.22e-46: 167: 47.46		SMCA5_HUMAN (19-1052): 0: 1097: 100.00
+	Hs
		229381 FOXL1_HUMAN (10-185): 3.38e-47: 164: 46.02		SMCA5_HUMAN (19-1052): 0: 1097: 100.00
+	Hs
		658652 FOXK2_HUMAN (2-324): 2.45e-54: 190: 22.42		SMCA1_HUMAN (71-1030): 0: 1042: 85.29
+	Hs
		658644 FOXG1_HUMAN (16-302): 2.94e-52: 181: 30.00		SMCA1_HUMAN (71-1030): 0: 1042: 85.29
+	Hs
		658661 FOXC1_HUMAN (5-181): 1.22e-46: 167: 47.46		SMCA1_HUMAN (71-1030): 0: 1042: 85.29
+	Hs
		658662 FOXL1_HUMAN (10-185): 3.38e-47: 164: 46.02		SMCA1_HUMAN (71-1030): 0: 1042: 85.29
+	Hs
		877716 FOXA1_HUMAN (5-312): 1.66e-62: 207: 28.25		CHD3_HUMAN (8-1052): 0: 801: 26.23
+	Hs
		877733 FOXA1_HUMAN (5-312): 1.66e-62: 207: 28.25		CHD4_HUMAN (14-945): 0: 769: 26.95
+	Hs
		964181 FOXK2_HUMAN (2-324): 2.45e-54: 190: 22.42		CHD4_HUMAN (14-945): 0: 769: 26.95
+	Hs
		877612 FOXG1_HUMAN (16-302): 2.94e-52: 181: 30.00		CHD4_HUMAN (14-945): 0: 769: 26.95
+	Hs
		1021109 FOXC1_HUMAN (5-181): 1.22e-46: 167: 47.46		CHD4_HUMAN (14-945): 0: 769: 26.95
+	Mm
		725295 FOXA2_MOUSE (1-289): 2.33e-51: 178: 26.96		SMCA4_MOUSE (63-936): 0: 725: 30.53
+	Hs
		1203230 FOXB1_HUMAN (6-323): 1.84e-54: 182: 32.30		CHD1L_HUMAN (175-867): 0: 711: 38.23
+	Hs
		846951 FOXC1_HUMAN (5-181): 1.22e-46: 167: 47.46		SMCA4_HUMAN (63-960): 0: 696: 29.09
+	Hs
		846765 FOXI1_HUMAN (17-252): 2.41e-48: 168: 35.42		SMCA2_HUMAN (161-654): 4.23e-122: 411: 44.02
+	Hs
		846764 FOXC1_HUMAN (5-181): 1.22e-46: 167: 47.46		SMCA2_HUMAN (161-654): 4.23e-122: 411: 44.02