HitPredict

Interactor 1: NCK2 (O43639)
Cytoplasmic protein NCK2 (Growth factor receptor-bound protein 4) (NCK adaptor protein 2) (Nck-2) (SH2/SH3 adaptor protein NCK-beta)
Gene: NCK2

Interactor 2: PRC2A (P48634)
Protein PRRC2A (HLA-B-associated transcript 2) (Large proline-rich protein BAT2) (Proline-rich and coiled-coil-containing protein 2A) (Protein G2)
Gene: PRRC2A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 380 Hs			1 2157
+	Hs
		820875 GRB2_HUMAN (3-61): 2.24e-18: 84.7: 28.81		PRC2A_HUMAN (1-2157): 4.11e-162: 555: 100.00
+	Hs
		557660 NCK1_HUMAN (1-379): 7.09e-91: 279: 68.24		ANK2_HUMAN (12-1866): 6e-46: 186: 11.09
+	Hs
		557777 NCK1_HUMAN (1-379): 7.09e-91: 279: 68.24		MINT_HUMAN (338-2157): 4.08e-29: 130: 10.26
+	Hs
		203208 NCK1_HUMAN (1-379): 7.09e-91: 279: 68.24		SYNJ1_HUMAN (746-1276): 8.4e-09: 63.4: 15.10
+	Hs
		411582 LCK_HUMAN (3-145): 6.3e-19: 90.2: 21.53		MUC1_HUMAN (1123-2148): 1.84e-48: 193: 12.03
+	Hs
		554292 GRB2_HUMAN (3-61): 2.24e-18: 84.7: 28.81		MUC1_HUMAN (1123-2148): 1.84e-48: 193: 12.03
+	Hs
		924484 GRB2_HUMAN (3-61): 2.24e-18: 84.7: 28.81		ANK2_HUMAN (12-1866): 6e-46: 186: 11.09
+	Hs
		782779 CSK_HUMAN (191-378): 3.44e-32: 127: 24.87		ZO1_HUMAN (265-982): 3.45e-30: 133: 13.23
+	Hs
		807680 GRB2_HUMAN (3-61): 2.24e-18: 84.7: 28.81		MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83
+	Hs
		655449 P85A_HUMAN (166-379): 4.05e-24: 106: 16.36		MINT_HUMAN (338-2157): 4.08e-29: 130: 10.26
+	Hs
		782839 CSK_HUMAN (191-378): 3.44e-32: 127: 24.87		NCOR2_HUMAN (550-2096): 1.47e-20: 102: 10.40
+	Hs
		990858 SH319_HUMAN (1-57): 2.18e-16: 82.8: 19.30		ZO1_HUMAN (265-982): 3.45e-30: 133: 13.23
+	Hs
		924808 GRB2_HUMAN (3-61): 2.24e-18: 84.7: 28.81		MINT_HUMAN (338-2157): 4.08e-29: 130: 10.26
+	Hs
		782820 CSK_HUMAN (191-378): 3.44e-32: 127: 24.87		CIC_HUMAN (8-701): 6.41e-09: 63.9: 8.78
+	Hs
		924473 GRB2_HUMAN (3-61): 2.24e-18: 84.7: 28.81		MAP1A_HUMAN (389-2155): 2.3e-14: 81.6: 8.60
+	Hs
		924760 GRB2_HUMAN (3-61): 2.24e-18: 84.7: 28.81		PRG4_HUMAN (775-1650): 2.91e-14: 81.1: 12.40
+	Hs
		203228 ITSN1_HUMAN (6-70): 3.77e-19: 91.7: 29.23		SYNJ1_HUMAN (746-1276): 8.4e-09: 63.4: 15.10
+	Hs
		203198 LCK_HUMAN (3-145): 6.3e-19: 90.2: 21.53		SYNJ1_HUMAN (746-1276): 8.4e-09: 63.4: 15.10
+	Hs
		203218 GRB2_HUMAN (3-61): 2.24e-18: 84.7: 28.81		SYNJ1_HUMAN (746-1276): 8.4e-09: 63.4: 15.10
+	Hs
		203230 SH319_HUMAN (1-57): 2.18e-16: 82.8: 19.30		SYNJ1_HUMAN (746-1276): 8.4e-09: 63.4: 15.10