HitPredict

Interactor 1: NCK2 (O43639)
Cytoplasmic protein NCK2 (Growth factor receptor-bound protein 4) (NCK adaptor protein 2) (Nck-2) (SH2/SH3 adaptor protein NCK-beta)
Gene: NCK2

Interactor 2: YLPM1 (P49750)
YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113)
Gene: YLPM1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 380 Hs			1 2146
+	Hs
		833048 ITSN2_HUMAN (3-309): 6.32e-28: 117: 18.31		YLPM1_HUMAN (1-2146): 0: 1062: 100.00
+	Hs
		832965 GRB2_HUMAN (3-61): 2.24e-18: 84.7: 28.81		YLPM1_HUMAN (1-2146): 0: 1062: 100.00
+	Hs
		557660 NCK1_HUMAN (1-379): 7.09e-91: 279: 68.24		ANK2_HUMAN (582-1637): 2.05e-12: 75.3: 8.49
+	Ce
		712432 Q95PW9_CAEEL (1-379): 5.2e-75: 239: 37.88		SC161_CAEEL (629-910): 2.89e-10: 68: 14.14
+	Hs
		411582 LCK_HUMAN (3-145): 6.3e-19: 90.2: 21.53		MUC1_HUMAN (3-539): 3.63e-15: 84: 10.85
+	Hs
		64077 SRC_HUMAN (203-361): 5.72e-16: 81.3: 31.55		L37A2_HUMAN (11-842): 1.19e-17: 92.3: 13.87
+	Hs
		554292 GRB2_HUMAN (3-61): 2.24e-18: 84.7: 28.81		MUC1_HUMAN (3-539): 3.63e-15: 84: 10.85
+	Hs
		522749 SRC_HUMAN (203-361): 5.72e-16: 81.3: 31.55		MUC1_HUMAN (3-539): 3.63e-15: 84: 10.85
+	Hs
		924484 GRB2_HUMAN (3-61): 2.24e-18: 84.7: 28.81		ANK2_HUMAN (582-1637): 2.05e-12: 75.3: 8.49
+	Hs
		1056926 SH3K1_HUMAN (8-109): 4.25e-16: 82: 16.35		MDC1_HUMAN (666-1573): 3.81e-11: 71: 9.78
+	Mm
		101430 CSK_MOUSE (2-134): 3.39e-11: 66.3: 17.04		F8VPR5_MOUSE (4-440): 7.51e-10: 66.8: 10.53