HitPredict

Interactor 1: NCK2 (O43639)
Cytoplasmic protein NCK2 (Growth factor receptor-bound protein 4) (NCK adaptor protein 2) (Nck-2) (SH2/SH3 adaptor protein NCK-beta)
Gene: NCK2

Interactor 2: CCDC6 (Q16204)
Coiled-coil domain-containing protein 6 (Papillary thyroid carcinoma-encoded protein) (Protein H4)
Gene: CCDC6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	38580884
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 380 Hs			1 474
+	Hs
		1078830 ITSN1_HUMAN (6-70): 3.77e-19: 91.7: 29.23		CCDC6_HUMAN (1-474): 2.18e-48: 174: 100.00
+	Hs
		412248 FYN_HUMAN (7-137): 2.1e-23: 103: 20.30		TAXB1_HUMAN (59-365): 6.01e-28: 119: 20.46
+	Hs
		1078919 ITSN2_HUMAN (3-309): 6.32e-28: 117: 18.31		ITSN1_HUMAN (14-474): 1.6e-22: 103: 11.38
+	Hs
		655386 P85A_HUMAN (166-379): 4.05e-24: 106: 16.36		ITSN1_HUMAN (14-474): 1.6e-22: 103: 11.38
+	Hs
		1078828 ITSN1_HUMAN (6-70): 3.77e-19: 91.7: 29.23		ITSN1_HUMAN (14-474): 1.6e-22: 103: 11.38
+	Hs
		411908 LCK_HUMAN (3-145): 6.3e-19: 90.2: 21.53		MRCKB_HUMAN (23-351): 2.44e-20: 96.6: 14.57
+	Hs
		1078886 SH3K1_HUMAN (8-109): 4.25e-16: 82: 16.35		ITSN1_HUMAN (14-474): 1.6e-22: 103: 11.38
+	Hs
		924566 GRB2_HUMAN (3-61): 2.24e-18: 84.7: 28.81		DCTN1_HUMAN (2-361): 1.64e-21: 100: 14.02
+	Hs
		1051309 SH319_HUMAN (1-57): 2.18e-16: 82.8: 19.30		DCTN1_HUMAN (2-361): 1.64e-21: 100: 14.02
+	Hs
		1349277 ITSN2_HUMAN (3-309): 6.32e-28: 117: 18.31		DAPLE_HUMAN (52-339): 4.11e-09: 61.2: 16.88
+	Hs
		412058 FYN_HUMAN (7-137): 2.1e-23: 103: 20.30		MYH9_HUMAN (4-401): 5.49e-12: 70.4: 11.78
+	Hs
		129220 P85B_HUMAN (21-380): 7.78e-23: 102: 13.10		MYH9_HUMAN (4-401): 5.49e-12: 70.4: 11.78
+	Hs
		412287 FYN_HUMAN (7-137): 2.1e-23: 103: 20.30		MY18A_HUMAN (62-328): 1.49e-10: 65.8: 15.87
+	Hs
		129221 P85B_HUMAN (21-380): 7.78e-23: 102: 13.10		MYH10_HUMAN (2-333): 9.28e-09: 60.4: 10.39
+	Hs
		724720 BLK_HUMAN (7-204): 3.35e-19: 91: 19.80		MYH9_HUMAN (4-401): 5.49e-12: 70.4: 11.78
+	Hs
		724756 GRB2_HUMAN (3-61): 2.24e-18: 84.7: 28.81		MYH9_HUMAN (4-401): 5.49e-12: 70.4: 11.78
+	Hs
		924736 GRB2_HUMAN (3-61): 2.24e-18: 84.7: 28.81		MY18A_HUMAN (62-328): 1.49e-10: 65.8: 15.87
+	Hs
		728465 GRB2_HUMAN (3-61): 2.24e-18: 84.7: 28.81		MYH11_HUMAN (54-323): 1.64e-09: 62.6: 17.07
+	Hs
		924586 GRB2_HUMAN (3-61): 2.24e-18: 84.7: 28.81		PLEC_HUMAN (67-346): 2.74e-09: 61.9: 11.79
+	Hs
		725134 GRB2_HUMAN (3-61): 2.24e-18: 84.7: 28.81		MYH10_HUMAN (2-333): 9.28e-09: 60.4: 10.39