HitPredict

Interactor 1: NCK2 (O43639)
Cytoplasmic protein NCK2 (Growth factor receptor-bound protein 4) (NCK adaptor protein 2) (Nck-2) (SH2/SH3 adaptor protein NCK-beta)
Gene: NCK2

Interactor 2: LRFN4 (Q6PJG9)
Leucine-rich repeat and fibronectin type-III domain-containing protein 4
Gene: LRFN4

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.80	0.765

Property	Details
Experiments	28514442, 33961781, 22677168
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	SH2~fn3, LRR_8~SH2
Common GO terms	-
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 380 Hs			1 635
+	Hs
		557718 NCK1_HUMAN (1-379): 7.09e-91: 279: 68.24		LRFN4_HUMAN (17-635): 1.88e-142: 430: 100.00
+	Hs
		655488 P85A_HUMAN (166-379): 4.05e-24: 106: 16.36		FLRT1_HUMAN (3-198): 1.1e-33: 138: 24.26
+	Hs
		129344 P85B_HUMAN (21-380): 7.78e-23: 102: 13.10		FLRT1_HUMAN (3-198): 1.1e-33: 138: 24.26
+	Hs
		433494 YES_HUMAN (6-120): 7.99e-16: 80.8: 23.08		FLRT1_HUMAN (3-198): 1.1e-33: 138: 24.26