HitPredict

Interactor 1: NCK2 (O43639)
Cytoplasmic protein NCK2 (Growth factor receptor-bound protein 4) (NCK adaptor protein 2) (Nck-2) (SH2/SH3 adaptor protein NCK-beta)
Gene: NCK2

Interactor 2: DAAF4 (Q8WXU2)
Dynein axonemal assembly factor 4 (Dyslexia susceptibility 1 candidate gene 1 protein)
Gene: DNAAF4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.657

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 380 Hs			1 420
+	Hs
		209162 NCK2_HUMAN (1-380): 6.88e-99: 300: 100.00		KLC2_HUMAN (51-418): 6.02e-42: 158: 12.89
+	Hs
		557619 NCK1_HUMAN (1-379): 7.09e-91: 279: 68.24		CDC27_HUMAN (40-419): 1.51e-44: 167: 13.52
+	Hs
		655229 P85A_HUMAN (166-379): 4.05e-24: 106: 16.36		CDC27_HUMAN (40-419): 1.51e-44: 167: 13.52
+	Hs
		412040 FYN_HUMAN (7-137): 2.1e-23: 103: 20.30		CDC27_HUMAN (40-419): 1.51e-44: 167: 13.52
+	Hs
		672805 GRB2_HUMAN (3-61): 2.24e-18: 84.7: 28.81		CDC27_HUMAN (40-419): 1.51e-44: 167: 13.52
+	Hs
		655282 P85A_HUMAN (166-379): 4.05e-24: 106: 16.36		PPP5_HUMAN (269-419): 9.35e-38: 145: 23.18
+	Hs
		672871 SH3K1_HUMAN (8-109): 4.25e-16: 82: 16.35		CDC27_HUMAN (40-419): 1.51e-44: 167: 13.52
+	Hs
		1285186 SH3K1_HUMAN (8-109): 4.25e-16: 82: 16.35		KLC2_HUMAN (51-418): 6.02e-42: 158: 12.89
+	Hs
		684476 CSK_HUMAN (191-378): 3.44e-32: 127: 24.87		STIP1_HUMAN (287-418): 3.89e-23: 103: 25.00
+	Hs
		858608 GRB2_HUMAN (3-61): 2.24e-18: 84.7: 28.81		PPP5_HUMAN (269-419): 9.35e-38: 145: 23.18
+	Hs
		411853 LCK_HUMAN (3-145): 6.3e-19: 90.2: 21.53		UN45A_HUMAN (272-412): 7.08e-33: 133: 29.86
+	Dm
		1366763 Q9VIF7_DROME (70-304): 4.01e-14: 76.3: 18.75		Q9VH81_DROME (257-419): 2.97e-37: 143: 22.70
+	Hs
		411617 LCK_HUMAN (3-145): 6.3e-19: 90.2: 21.53		STIP1_HUMAN (287-418): 3.89e-23: 103: 25.00
+	Hs
		411735 LCK_HUMAN (3-145): 6.3e-19: 90.2: 21.53		TOM34_HUMAN (282-416): 2.07e-19: 90: 26.57
+	Hs
		174558 YES_HUMAN (6-120): 7.99e-16: 80.8: 23.08		OGT1_HUMAN (93-378): 1.39e-19: 93.5: 11.29