HitPredict

Interactor 1: PLRG1 (O43660)
Pleiotropic regulator 1
Gene: PLRG1

Interactor 2: RC3H2 (Q9HBD1)
Roquin-2 (EC 2.3.2.27) (Membrane-associated nucleic acid-binding protein) (RING finger and CCCH-type zinc finger domain-containing protein 2) (RING finger protein 164) (RING-type E3 ubiquitin transferase Roquin-2)
Gene: RC3H2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	30209976
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	WD40~zf-CCCH
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 514 Hs			1 1191
+	Hs
		1288313 SNR40_HUMAN (26-356): 1.15e-62: 210: 17.51		RC3H2_HUMAN (1-1191): 0: 1105: 100.00
+	Hs
		209451 PLRG1_HUMAN (1-514): 1.02e-144: 427: 100.00		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		197090 PRP4_HUMAN (200-398): 1.15e-15: 81.6: 26.87		RC3H2_HUMAN (1-1191): 0: 1105: 100.00
+	Hs
		1136222 SNR40_HUMAN (26-356): 1.15e-62: 210: 17.51		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		209436 PLRG1_HUMAN (1-514): 1.02e-144: 427: 100.00		MDC1_HUMAN (442-806): 1.14e-11: 71.8: 12.21
+	Sp
		999840 TUP11_SCHPO (229-514): 1.67e-77: 256: 19.33		LKH1_SCHPO (527-814): 6.12e-09: 62.2: 14.78
+	Sp
		1013593 TUP12_SCHPO (237-512): 1.12e-71: 240: 21.88		LKH1_SCHPO (527-814): 6.12e-09: 62.2: 14.78
+	Hs
		1056932 SNR40_HUMAN (26-356): 1.15e-62: 210: 17.51		MDC1_HUMAN (442-806): 1.14e-11: 71.8: 12.21
+	Hs
		903374 WDR5_HUMAN (20-315): 8.55e-56: 191: 13.06		KMT2C_HUMAN (351-895): 4.49e-14: 79.7: 9.35
+	Mm
		903669 WDR5_MOUSE (20-315): 8.55e-56: 191: 13.06		KMT2C_MOUSE (400-893): 7.11e-11: 69.2: 9.42
+	Hs
		903405 WDR5_HUMAN (20-315): 8.55e-56: 191: 13.06		CBP_HUMAN (556-893): 1.74e-09: 64.6: 9.77
+	Dm
		113977 GBLP_DROME (318-500): 7.62e-35: 134: 21.65		M9PB30_DROME (683-1171): 5.39e-11: 69.7: 12.25