HitPredict

Interactor 1: PRC1 (O43663)
Protein regulator of cytokinesis 1
Gene: PRC1

Interactor 2: H2AY (O75367)
Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (Histone H2A.y) (H2A/y) (Medulloblastoma antigen MU-MB-50.205)
Gene: MACROH2A1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31586073
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0019901 - protein kinase binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 620 Hs			1 369
+	Hs
		210339 PRC1_HUMAN (1-620): 2.12e-153: 457: 100.00		H2AW_HUMAN (1-368): 1.41e-145: 418: 66.04
+	Hs
		209642 PRC1_HUMAN (1-620): 2.12e-153: 457: 100.00		H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69
+	Hs
		210112 PRC1_HUMAN (1-620): 2.12e-153: 457: 100.00		H2A2B_HUMAN (1-125): 5.78e-65: 204: 64.06
+	Hs
		209582 PRC1_HUMAN (1-620): 2.12e-153: 457: 100.00		H2A1B_HUMAN (1-126): 1.27e-64: 203: 62.02
+	Hs
		209613 PRC1_HUMAN (1-620): 2.12e-153: 457: 100.00		H2A1_HUMAN (1-126): 1.21e-64: 203: 62.02
+	Hs
		210032 PRC1_HUMAN (1-620): 2.12e-153: 457: 100.00		H2A2C_HUMAN (1-125): 9.23e-64: 201: 63.28
+	Sc
		392502 ASE1_YEAST (151-555): 3.47e-57: 209: 20.54		H2A2_YEAST (14-123): 1.54e-41: 144: 67.27
+	Sc
		392156 ASE1_YEAST (151-555): 3.47e-57: 209: 20.54		H2A1_YEAST (14-123): 2.85e-41: 143: 67.27