HitPredict

Interactor 1: NDUB5 (O43674)
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (Complex I-SGDH) (CI-SGDH) (NADH-ubiquinone oxidoreductase SGDH subunit)
Gene: NDUFB5

Interactor 2: NDUC2 (O95298)
NADH dehydrogenase [ubiquinone] 1 subunit C2 (Complex I-B14.5b) (CI-B14.5b) (Human lung cancer oncogene 1 protein) (HLC-1) (NADH-ubiquinone oxidoreductase subunit B14.5b)
Gene: NDUFC2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.895

The method score is based on:

Property Details
Experiments 33961781, 28514442, 35235311, 37071682
Identification Methods affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains NDUF_B5~NDUF_C2
Common GO terms GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0006120 - mitochondrial electron transport, NADH to ubiquinone
GO:0008137 - NADH dehydrogenase (ubiquinone) activity
GO:0009060 - aerobic respiration
and 2 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 189
Hs

1 119
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024