HitPredict

Interactor 1: BUB1 (O43683)
Mitotic checkpoint serine/threonine-protein kinase BUB1 (hBUB1) (EC 2.7.11.1) (BUB1A)
Gene: BUB1

Interactor 2: ZYX (Q15942)
Zyxin (Zyxin-2)
Gene: ZYX

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1085 Hs			1 572
+	Hs
		236937 BUB1B_HUMAN (2-1078): 1.02e-166: 521: 19.02		ZYX_HUMAN (1-572): 1.68e-71: 241: 100.00
+	Hs
		325748 LATS1_HUMAN (111-1077): 6.55e-119: 395: 10.17		ZYX_HUMAN (1-572): 1.68e-71: 241: 100.00
+	Hs
		325930 LATS1_HUMAN (111-1077): 6.55e-119: 395: 10.17		LIMD1_HUMAN (1-571): 7.16e-66: 228: 22.80
+	Hs
		325743 LATS1_HUMAN (111-1077): 6.55e-119: 395: 10.17		TRIP6_HUMAN (63-571): 6e-66: 224: 32.82
+	Hs
		166561 DCLK1_HUMAN (396-1075): 1.55e-121: 392: 12.97		TRIP6_HUMAN (63-571): 6e-66: 224: 32.82
+	Hs
		166591 DCLK1_HUMAN (396-1075): 1.55e-121: 392: 12.97		FBLI1_HUMAN (252-572): 4.13e-67: 224: 29.61
+	Hs
		1234193 DCLK2_HUMAN (388-1075): 1.52e-119: 387: 11.59		FBLI1_HUMAN (252-572): 4.13e-67: 224: 29.61
+	Hs
		236969 BUB1B_HUMAN (2-1078): 1.02e-166: 521: 19.02		AJUBA_HUMAN (9-499): 2.93e-13: 74.3: 11.33
+	Hs
		63200 LATS1_HUMAN (111-1077): 6.55e-119: 395: 10.17		WTIP_HUMAN (196-571): 8.71e-56: 195: 28.08
+	Hs
		1039069 KCC2D_HUMAN (774-1085): 1.18e-103: 336: 14.29		ZYX_HUMAN (1-572): 1.68e-71: 241: 100.00
+	Hs
		1039129 KCC2D_HUMAN (774-1085): 1.18e-103: 336: 14.29		FBLI1_HUMAN (252-572): 4.13e-67: 224: 29.61
+	Hs
		160831 AURKA_HUMAN (654-1065): 8.12e-81: 271: 15.09		LIMD1_HUMAN (1-571): 7.16e-66: 228: 22.80
+	Hs
		160585 AURKA_HUMAN (654-1065): 8.12e-81: 271: 15.09		TRIP6_HUMAN (63-571): 6e-66: 224: 32.82
+	Hs
		238959 PAK1_HUMAN (584-1085): 3.96e-95: 315: 16.97		LPXN_HUMAN (221-570): 4.84e-47: 170: 18.75
+	Hs
		325852 LATS1_HUMAN (111-1077): 6.55e-119: 395: 10.17		AJUBA_HUMAN (9-499): 2.93e-13: 74.3: 11.33
+	Hs
		238960 PAK2_HUMAN (581-1085): 4.98e-84: 284: 15.37		LPXN_HUMAN (221-570): 4.84e-47: 170: 18.75
+	Hs
		823381 PAK1_HUMAN (584-1085): 3.96e-95: 315: 16.97		PAXI_HUMAN (8-500): 3.72e-32: 132: 12.12
+	Mm
		103576 G5E884_MOUSE (584-1085): 8.24e-97: 319: 16.82		PAXI_MOUSE (8-500): 1.2e-28: 122: 12.43
+	Hs
		823382 PAK2_HUMAN (581-1085): 4.98e-84: 284: 15.37		PAXI_HUMAN (8-500): 3.72e-32: 132: 12.12
+	Hs
		160710 AURKA_HUMAN (654-1065): 8.12e-81: 271: 15.09		AJUBA_HUMAN (9-499): 2.93e-13: 74.3: 11.33