HitPredict

Interactor 1: BUB1 (O43683)
Mitotic checkpoint serine/threonine-protein kinase BUB1 (hBUB1) (EC 2.7.11.1) (BUB1A)
Gene: BUB1

Interactor 2: AP4B1 (Q9Y6B7)
AP-4 complex subunit beta-1 (AP-4 adaptor complex subunit beta) (Adaptor-related protein complex 4 subunit beta-1) (Beta subunit of AP-4) (Beta4-adaptin)
Gene: AP4B1

Species: Homo sapiens

Source: dip

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	12419313
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1085 Hs			1 739
+	Hs
		211006 BUB1_HUMAN (1-1085): 0: 829: 100.00		AP1B1_HUMAN (3-614): 0: 567: 29.03
+	Hs
		119891 BUB1_HUMAN (1-1085): 0: 829: 100.00		AP3B1_HUMAN (4-587): 3.69e-151: 470: 21.68
+	Hs
		237001 BUB1B_HUMAN (2-1078): 1.02e-166: 521: 19.02		AP4B1_HUMAN (1-739): 0: 717: 100.00
+	Hs
		236908 BUB1B_HUMAN (2-1078): 1.02e-166: 521: 19.02		AP2B1_HUMAN (3-611): 0: 576: 28.53
+	Hs
		236917 BUB1B_HUMAN (2-1078): 1.02e-166: 521: 19.02		AP1B1_HUMAN (3-614): 0: 567: 29.03
+	Dm
		1096910 Q9VMS5_DROME (1-1073): 3.25e-141: 454: 17.38		Q24253_DROME (3-632): 0: 563: 28.17
+	Hs
		119894 BUB1B_HUMAN (2-1078): 1.02e-166: 521: 19.02		AP3B1_HUMAN (4-587): 3.69e-151: 470: 21.68
+	Hs
		212600 AKT2_HUMAN (743-1084): 3.35e-115: 366: 11.90		AP1G1_HUMAN (6-614): 1.44e-164: 496: 13.96
+	Dm
		51396 A1Z6I7_DROME (4-319): 1.92e-66: 247: 24.56		Q24253_DROME (3-632): 0: 563: 28.17
+	Hs
		302146 KCC2D_HUMAN (774-1085): 1.18e-103: 336: 14.29		AP2A2_HUMAN (5-629): 4.87e-145: 449: 14.62
+	Hs
		160880 AURKA_HUMAN (654-1065): 8.12e-81: 271: 15.09		COPG1_HUMAN (31-522): 2.07e-75: 263: 17.00