Interactor 1: BUB3 (O43684)
Mitotic checkpoint protein BUB3
Gene: BUB3
Interactor 2: BUB1B (O60566)
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (MAD3/BUB1-related protein kinase) (hBUBR1) (Mitotic checkpoint kinase MAD3L) (Protein SSK1)
Gene: BUB1B
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.98 | 1.00 | 0.994 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26186194, 26496610, 28514442, 9660858, 33961781, 35217622, 20220147, 25246557, 25852190, 25833949, 25505175, 25669885, 25482201, 24151075, 28410192, 27939943, 28404789, 11535616, 12419313, 32152539 and 12 others
more... |
| Identification Methods | affinity chromatography technology, two hybrid, pull down, biochemical, anti tag coimmunoprecipitation, mammalian protein protein interaction trap, two hybrid array |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Mad3_BUB1_I~WD40 |
| Common GO terms | GO:0000776 - kinetochore GO:0005829 - cytosol GO:0007094 - mitotic spindle assembly checkpoint signaling GO:0033597 - mitotic checkpoint complex GO:0051301 - cell division |
| Homologous interactions | 16 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
