HitPredict

Interactor 1: BUB3 (O43684)
Mitotic checkpoint protein BUB3
Gene: BUB3

Interactor 2: THA (P10827)
Thyroid hormone receptor alpha (Nuclear receptor subfamily 1 group A member 1) (V-erbA-related protein 7) (EAR-7) (c-erbA-1) (c-erbA-alpha)
Gene: THRA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	21988832
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 328 Hs			1 490
+	Hs
		369669 TAF5_HUMAN (65-295): 2.05e-24: 105: 18.35		ESR1_HUMAN (1-442): 2.2e-108: 336: 19.04
+	Hs
		782550 TAF5_HUMAN (65-295): 2.05e-24: 105: 18.35		HNF4A_HUMAN (8-451): 1.23e-104: 322: 21.87
+	Hs
		369305 WDR5_HUMAN (209-320): 6.93e-20: 90.4: 16.07		ESR1_HUMAN (1-442): 2.2e-108: 336: 19.04
+	Hs
		369932 WDR5B_HUMAN (208-320): 1.06e-19: 89.7: 16.81		ESR1_HUMAN (1-442): 2.2e-108: 336: 19.04
+	Hs
		488008 SNR40_HUMAN (1-121): 1.07e-23: 101: 17.42		RARA_HUMAN (12-406): 7.57e-104: 319: 31.31
+	Hs
		782513 WDR5_HUMAN (209-320): 6.93e-20: 90.4: 16.07		HNF4A_HUMAN (8-451): 1.23e-104: 322: 21.87
+	Mm
		903664 WDR5_MOUSE (209-320): 6.93e-20: 90.4: 16.07		ERR2_MOUSE (1-409): 3.66e-101: 312: 21.41
+	Hs
		903650 WDR5_HUMAN (209-320): 6.93e-20: 90.4: 16.07		NR2E3_HUMAN (1-407): 7.49e-100: 307: 23.15
+	Hs
		267731 TAF5L_HUMAN (17-146): 4.7e-09: 59.3: 36.23		ESR1_HUMAN (1-442): 2.2e-108: 336: 19.04
+	Hs
		267744 TAF5L_HUMAN (17-146): 4.7e-09: 59.3: 36.23		HNF4A_HUMAN (8-451): 1.23e-104: 322: 21.87
+	Hs
		740487 WDR5_HUMAN (209-320): 6.93e-20: 90.4: 16.07		PPARG_HUMAN (52-378): 9.25e-32: 129: 30.70