HitPredict

Interactor 1: BUB3 (O43684)
Mitotic checkpoint protein BUB3
Gene: BUB3

Interactor 2: SET1B (Q9UPS6)
Histone-lysine N-methyltransferase SETD1B (EC 2.1.1.364) (Lysine N-methyltransferase 2G) (SET domain-containing protein 1B) (hSET1B)
Gene: SETD1B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	N-SET~WD40
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 328 Hs			1 1966
+	Hs
		211281 BUB3_HUMAN (1-328): 4.65e-94: 284: 100.00		KMT2B_HUMAN (1069-1966): 4.68e-71: 268: 21.69
+	Hs
		211161 BUB3_HUMAN (1-328): 4.65e-94: 284: 100.00		KMT2A_HUMAN (1173-1966): 2.68e-66: 252: 21.73
+	Hs
		211190 BUB3_HUMAN (1-328): 4.65e-94: 284: 100.00		EZH2_HUMAN (1464-1949): 9.8e-64: 235: 15.84
+	Hs
		211213 BUB3_HUMAN (1-328): 4.65e-94: 284: 100.00		KMT2C_HUMAN (1759-1966): 1.32e-58: 227: 37.04
+	Hs
		165604 BUB3_HUMAN (1-328): 4.65e-94: 284: 100.00		SET1A_HUMAN (409-1966): 1e-54: 214: 22.13
+	Hs
		975303 FBXW7_HUMAN (1-202): 6.93e-47: 169: 20.85		KMT2A_HUMAN (1173-1966): 2.68e-66: 252: 21.73
+	Dm
		113998 Q9W1T0_DROME (2-315): 6.17e-99: 296: 26.32		M9PB30_DROME (158-890): 1.8e-23: 111: 13.06
+	Hs
		1080207 FBXW7_HUMAN (1-202): 6.93e-47: 169: 20.85		EZH2_HUMAN (1464-1949): 9.8e-64: 235: 15.84
+	Hs
		1317584 NLE1_HUMAN (86-326): 2.9e-49: 172: 13.10		SETD2_HUMAN (1733-1965): 3.5e-58: 225: 24.07
+	Zm
		35725 A0A1D6LQJ4_MAIZE (1-205): 4.05e-47: 163: 15.14		A0A1D6M742_MAIZE (1624-1963): 4.63e-62: 228: 17.44
+	Hs
		152559 BUB3_HUMAN (1-328): 4.65e-94: 284: 100.00		KMT2D_HUMAN (1826-1966): 3.07e-17: 91.3: 46.85
+	Hs
		1288387 SNR40_HUMAN (1-121): 1.07e-23: 101: 17.42		KMT2B_HUMAN (1069-1966): 4.68e-71: 268: 21.69
+	Hs
		1288292 SNR40_HUMAN (1-121): 1.07e-23: 101: 17.42		NSD3_HUMAN (1721-1965): 3.64e-68: 256: 24.90
+	Hs
		975304 SNR40_HUMAN (1-121): 1.07e-23: 101: 17.42		KMT2A_HUMAN (1173-1966): 2.68e-66: 252: 21.73
+	Hs
		331862 SNR40_HUMAN (1-121): 1.07e-23: 101: 17.42		NSD2_HUMAN (1654-1965): 6.33e-60: 230: 22.15
+	Hs
		1288291 SNR40_HUMAN (1-121): 1.07e-23: 101: 17.42		SETD2_HUMAN (1733-1965): 3.5e-58: 225: 24.07
+	Mm
		903669 WDR5_MOUSE (209-320): 6.93e-20: 90.4: 16.07		KMT2C_MOUSE (1759-1966): 6.65e-58: 225: 36.57
+	Hs
		165657 WDR5_HUMAN (209-320): 6.93e-20: 90.4: 16.07		SET1A_HUMAN (409-1966): 1e-54: 214: 22.13
+	Hs
		152678 FBXW7_HUMAN (1-202): 6.93e-47: 169: 20.85		KMT2D_HUMAN (1826-1966): 3.07e-17: 91.3: 46.85
+	Hs
		152622 WDR5_HUMAN (209-320): 6.93e-20: 90.4: 16.07		KMT2D_HUMAN (1826-1966): 3.07e-17: 91.3: 46.85