HitPredict

Interactor 1: AKA7A (O43687)
A-kinase anchor protein 7 isoforms alpha and beta (AKAP-7 isoforms alpha and beta) (A-kinase anchor protein 18 kDa) (AKAP 18) (Protein kinase A-anchoring protein 7 isoforms alpha/beta) (PRKA7 isoforms alpha/beta)
Gene: AKAP7

Interactor 2: KAP3 (P31323)
cAMP-dependent protein kinase type II-beta regulatory subunit
Gene: PRKAR2B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.59	1.00	0.769

Property	Details
Experiments	unassigned1304, 33961781
Identification Methods	two hybrid array, validated two hybrid, two hybrid prey pooling approach, anti tag coimmunoprecipitation, mammalian protein protein interaction trap
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	AKAP7_RIRII_bdg~RIIa
Common GO terms	GO:0005886 - plasma membrane GO:0035556 - intracellular signal transduction
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 104 Hs			1 418
+	Hs
		211307 AKA7A_HUMAN (1-104): 1.4e-58: 176: 100.00		Q6DHZ2_HUMAN (1-418): 9.29e-141: 409: 99.76
+	Hs
		211290 AKA7A_HUMAN (1-104): 1.4e-58: 176: 100.00		KAP2_HUMAN (3-413): 1.93e-125: 370: 64.81
+	Hs
		679405 AKA7G_HUMAN (40-104): 9.28e-36: 126: 100.00		KAP3_HUMAN (1-418): 3.91e-140: 408: 100.00
+	Hs
		533882 AKA7G_HUMAN (40-104): 9.28e-36: 126: 100.00		KAP2_HUMAN (3-413): 1.93e-125: 370: 64.81
+	Hs
		211294 AKA7A_HUMAN (1-104): 1.4e-58: 176: 100.00		KAP1_HUMAN (102-276): 7.34e-24: 104: 25.84
+	Hs
		211289 AKA7A_HUMAN (1-104): 1.4e-58: 176: 100.00		KAP0_HUMAN (102-276): 8.25e-24: 103: 24.72
+	Hs
		679320 AKA7G_HUMAN (40-104): 9.28e-36: 126: 100.00		KAP1_HUMAN (102-276): 7.34e-24: 104: 25.84
+	Hs
		498365 AKA7G_HUMAN (40-104): 9.28e-36: 126: 100.00		KAP0_HUMAN (102-276): 8.25e-24: 103: 24.72