Interactor 1: ACTN4 (O43707)
Alpha-actinin-4 (Non-muscle alpha-actinin 4)
Gene: ACTN4

Interactor 2: SRC (P12931)
Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
Gene: SRC

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.737

The method score is based on:

Property Details
Experiments 31980649, unassigned2173
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains CH~PK_Tyr_Ser-Thr
Common GO terms GO:0005178 - integrin binding
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0005925 - focal adhesion
GO:0030054 - cell junction
and 3 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 911
Hs

1 536
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024