Interactor 1: ACTN4 (O43707)
Alpha-actinin-4 (Non-muscle alpha-actinin 4)
Gene: ACTN4
Interactor 2: ZO1 (Q07157)
Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1)
Gene: TJP1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.51 | 1.00 | 0.715 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 16944923 |
| Identification Methods | affinity chromatography technology, pull down, anti bait coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Spectrin~ZU5 |
| Common GO terms | GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0030036 - actin cytoskeleton organization GO:0030054 - cell junction GO:0030335 - positive regulation of cell migration and 2 others more... |
| Homologous interactions | 12 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
