HitPredict

Interactor 1: ACTN4 (O43707)
Alpha-actinin-4 (Non-muscle alpha-actinin 4)
Gene: ACTN4

Interactor 2: ECT2 (Q9H8V3)
Protein ECT2 (Epithelial cell-transforming sequence 2 oncogene)
Gene: ECT2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31586073
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0015031 - protein transport GO:0042803 - protein homodimerization activity
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 911 Hs			1 914
+	Hs
		521615 ACTN1_HUMAN (20-911): 0: 607: 85.76		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		993295 ACTN3_HUMAN (37-911): 0: 567: 74.51		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		725699 ACTN2_HUMAN (19-911): 0: 556: 77.16		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		1329039 SPTN4_HUMAN (244-822): 1.07e-13: 77.8: 11.00		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		963418 SPTB2_HUMAN (215-825): 5.91e-11: 68.9: 10.75		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		164666 SPTN2_HUMAN (262-846): 1.08e-09: 64.7: 12.62		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		506843 SPTB1_HUMAN (213-819): 7.03e-09: 62: 10.57		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		963335 SPTB2_HUMAN (215-825): 5.91e-11: 68.9: 10.75		ITSN1_HUMAN (402-782): 1.02e-76: 276: 18.14