Interactor 1: BUD23 (O43709)
Probable 18S rRNA (guanine-N(7))-methyltransferase (EC 2.1.1.-) (Bud site selection protein 23 homolog) (Metastasis-related methyltransferase 1) (Williams-Beuren syndrome chromosomal region 22 protein) (rRNA methyltransferase and ribosome maturation factor)
Gene: BUD23
Interactor 2: TR112 (Q9UI30)
Multifunctional methyltransferase subunit TRM112-like protein (tRNA methyltransferase 112 homolog)
Gene: TRMT112
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.93 | 1.00 | 0.967 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26186194, 26472760, 28514442, 32296183, 33961781, unassigned1304, 34948388, 25851604 |
| Identification Methods | affinity chromatography technology, two hybrid, two hybrid prey pooling approach, two hybrid array, anti tag coimmunoprecipitation, validated two hybrid, pull down |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Methyltransf_11~Trm112p |
| Common GO terms | GO:0005654 - nucleoplasm GO:0046982 - protein heterodimerization activity GO:0048471 - perinuclear region of cytoplasm GO:0070476 - rRNA (guanine-N7)-methylation GO:2000234 - positive regulation of rRNA processing |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
