HitPredict

Interactor 1: TLX3 (O43711)
T-cell leukemia homeobox protein 3 (Homeobox protein Hox-11L2)
Gene: TLX3

Interactor 2: TLE3 (Q04726)
Transducin-like enhancer protein 3 (Enhancer of split groucho-like protein 3) (ESG3)
Gene: TLE3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 291 Hs			1 772
+	Hs
		679097 TLX1_HUMAN (2-290): 2.68e-37: 136: 54.30		TLE3_HUMAN (1-772): 0: 583: 100.00
+	Hs
		211837 TLX3_HUMAN (1-291): 5.64e-54: 179: 100.00		TLE1_HUMAN (1-772): 0: 538: 77.42
+	Hs
		211840 TLX3_HUMAN (1-291): 5.64e-54: 179: 100.00		TLE4_HUMAN (1-772): 9.37e-179: 533: 80.65
+	Hs
		678903 HXC8_HUMAN (52-229): 4.66e-35: 128: 23.46		TLE3_HUMAN (1-772): 0: 583: 100.00
+	Hs
		620143 PAX7_HUMAN (9-282): 6.05e-32: 125: 15.77		TLE3_HUMAN (1-772): 0: 583: 100.00
+	Mm
		526710 MSX1_MOUSE (46-242): 2.45e-45: 156: 26.70		TLE4_MOUSE (1-772): 6.16e-179: 533: 80.77
+	Hs
		679096 TLX1_HUMAN (2-290): 2.68e-37: 136: 54.30		TLE1_HUMAN (1-772): 0: 538: 77.42
+	Hs
		679098 TLX1_HUMAN (2-290): 2.68e-37: 136: 54.30		TLE4_HUMAN (1-772): 9.37e-179: 533: 80.65
+	Hs
		620142 PAX7_HUMAN (9-282): 6.05e-32: 125: 15.77		TLE1_HUMAN (1-772): 0: 538: 77.42
+	Hs
		211838 TLX3_HUMAN (1-291): 5.64e-54: 179: 100.00		TLE2_HUMAN (1-772): 4.46e-145: 445: 62.10
+	Hs
		658626 MSX1_HUMAN (46-242): 8.37e-50: 168: 29.13		TLE2_HUMAN (1-772): 4.46e-145: 445: 62.10
+	Hs
		211844 TLX3_HUMAN (1-291): 5.64e-54: 179: 100.00		TLE5_HUMAN (1-200): 1.22e-100: 310: 62.19
+	Mm
		526708 MSX1_MOUSE (46-242): 2.45e-45: 156: 26.70		TLE5_MOUSE (1-200): 2.63e-100: 309: 61.69
+	Hs
		679101 TLX1_HUMAN (2-290): 2.68e-37: 136: 54.30		TLE5_HUMAN (1-200): 1.22e-100: 310: 62.19
+	Hs
		678908 HXC8_HUMAN (52-229): 4.66e-35: 128: 23.46		TLE5_HUMAN (1-200): 1.22e-100: 310: 62.19
+	Hs
		211960 TLX3_HUMAN (1-291): 5.64e-54: 179: 100.00		TBL1R_HUMAN (571-771): 3.06e-46: 174: 15.07
+	Mm
		223203 TLX3_MOUSE (1-291): 6.02e-54: 179: 99.66		TLE6_MOUSE (473-772): 7.97e-46: 174: 33.66
+	Hs
		211820 TLX3_HUMAN (1-291): 5.64e-54: 179: 100.00		WDR5_HUMAN (284-560): 2.42e-32: 130: 9.12
+	Mm
		678773 HXA2_MOUSE (50-235): 3.31e-35: 131: 25.13		TLE6_MOUSE (473-772): 7.97e-46: 174: 33.66
+	Hs
		620138 PAX7_HUMAN (9-282): 6.05e-32: 125: 15.77		WDR5_HUMAN (284-560): 2.42e-32: 130: 9.12