HitPredict

Interactor 1: TLX3 (O43711)
T-cell leukemia homeobox protein 3 (Homeobox protein Hox-11L2)
Gene: TLX3

Interactor 2: NIPBL (Q6KC79)
Nipped-B-like protein (Delangin) (SCC2 homolog)
Gene: NIPBL

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 291 Hs			1 2804
+	Hs
		679119 TLX1_HUMAN (2-290): 2.68e-37: 136: 54.30		NIPBL_HUMAN (1-2804): 0: 2316: 100.00
+	Hs
		213344 TLX2_HUMAN (11-290): 4.67e-32: 121: 58.87		NIPBL_HUMAN (1-2804): 0: 2316: 100.00
+	Hs
		211919 TLX3_HUMAN (1-291): 5.64e-54: 179: 100.00		KMT2C_HUMAN (291-1338): 6.93e-10: 67.5: 8.63
+	Hs
		152560 TLX3_HUMAN (1-291): 5.64e-54: 179: 100.00		KMT2D_HUMAN (6-887): 4.25e-09: 64.8: 10.15
+	Hs
		679137 TLX1_HUMAN (2-290): 2.68e-37: 136: 54.30		KMT2C_HUMAN (291-1338): 6.93e-10: 67.5: 8.63
+	Hs
		152596 TLX1_HUMAN (2-290): 2.68e-37: 136: 54.30		KMT2D_HUMAN (6-887): 4.25e-09: 64.8: 10.15
+	Hs
		620175 PAX7_HUMAN (9-282): 6.05e-32: 125: 15.77		KMT2C_HUMAN (291-1338): 6.93e-10: 67.5: 8.63
+	Hs
		152588 PAX7_HUMAN (9-282): 6.05e-32: 125: 15.77		KMT2D_HUMAN (6-887): 4.25e-09: 64.8: 10.15
+	Hs
		213358 TLX2_HUMAN (11-290): 4.67e-32: 121: 58.87		KMT2C_HUMAN (291-1338): 6.93e-10: 67.5: 8.63
+	Hs
		152561 TLX2_HUMAN (11-290): 4.67e-32: 121: 58.87		KMT2D_HUMAN (6-887): 4.25e-09: 64.8: 10.15
+	Hs
		839785 LHX2_HUMAN (77-290): 3.21e-29: 116: 18.10		KMT2C_HUMAN (291-1338): 6.93e-10: 67.5: 8.63
+	Hs
		152615 LHX2_HUMAN (77-290): 3.21e-29: 116: 18.10		KMT2D_HUMAN (6-887): 4.25e-09: 64.8: 10.15