HitPredict

Interactor 1: TRIA1 (O43715)
TP53-regulated inhibitor of apoptosis 1 (Protein 15E1.1) (WF-1) (p53-inducible cell-survival factor) (p53CSV)
Gene: TRIAP1

Interactor 2: PRLD1 (Q9Y255)
PRELI domain-containing protein 1, mitochondrial (25 kDa protein of relevant evolutionary and lymphoid interest) (Px19-like protein)
Gene: PRELID1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	1.00	0.919

The method score is based on:

Property	Details
Experiments	28514442, 33961781, 26186194, 27499296, 30850607
Identification Methods	affinity chromatography technology, x-ray crystallography, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	PRELI~UPF0203
Common GO terms	GO:0005654 - nucleoplasm GO:0005739 - mitochondrion GO:0005758 - mitochondrial intermembrane space GO:0006915 - apoptotic process GO:0015914 - phospholipid transport and 6 others more... GO:0032991 - protein-containing complex GO:0043066 - negative regulation of apoptotic process GO:0090201 - negative regulation of release of cytochrome c from mitochondria GO:0097035 - regulation of membrane lipid distribution GO:1990050 - phosphatidic acid transfer activity GO:2001140 - positive regulation of phospholipid transport
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1	76
Hs

1	219

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024