Interactor 1: HTSF1 (O43719)
17S U2 SnRNP complex component HTATSF1 (HIV Tat-specific factor 1) (Tat-SF1)
Gene: HTATSF1

Interactor 2: SF3B1 (O75533)
Splicing factor 3B subunit 1 (Pre-mRNA-splicing factor SF3b 155 kDa subunit) (SF3b155) (Spliceosome-associated protein 155) (SAP 155)
Gene: SF3B1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.70 1.00 0.840

The method score is based on:

Property Details
Experiments 35271311, 30567737
Identification Methods affinity chromatography technology, pull down, isothermal titration calorimetry, anti bait coimmunoprecipitation, x-ray crystallography, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains RRM_1~SF3b1
Common GO terms GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005681 - spliceosomal complex
and 3 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 755
Hs

1 1304
+ Hs
+ Hs
+ Hs
+ Sp
+ Sc
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024