HitPredict

Interactor 1: HTSF1 (O43719)
17S U2 SnRNP complex component HTATSF1 (HIV Tat-specific factor 1) (Tat-SF1)
Gene: HTATSF1

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35063084
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 755 Hs			1 758
+	Hs
		496346 ELAV4_HUMAN (88-420): 8.56e-36: 141: 13.20		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496937 ELAV2_HUMAN (117-424): 7.45e-35: 138: 13.06		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496344 U2AF2_HUMAN (129-356): 2.97e-32: 133: 22.03		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496957 PABP4_HUMAN (62-285): 4.99e-31: 131: 12.66		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496405 TIA1_HUMAN (127-364): 1.82e-31: 129: 16.12		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496179 PABP1_HUMAN (62-264): 9.56e-30: 127: 12.14		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		497082 ELAV1_HUMAN (133-381): 1.21e-29: 122: 15.69		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Mm
		498054 Q62029_MOUSE (131-458): 6.95e-36: 146: 12.37		TAU_MOUSE (1-758): 1.4e-69: 244: 70.17
+	Rn
		582032 PABP1_RAT (62-264): 1.23e-29: 127: 12.14		TAU_RAT (1-758): 4.86e-75: 260: 71.47
+	Rn
		94258 PABP1_RAT (62-264): 1.23e-29: 127: 12.14		F1LST4_RAT (1-757): 8.59e-75: 260: 71.56
+	Mm
		498050 ELAV4_MOUSE (88-420): 6.49e-36: 141: 13.20		TAU_MOUSE (1-758): 1.4e-69: 244: 70.17
+	Hs
		496876 EWS_HUMAN (126-217): 8.36e-16: 83.3: 26.60		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Mm
		497953 TIA1_MOUSE (127-376): 1.76e-31: 129: 15.75		TAU_MOUSE (1-758): 1.4e-69: 244: 70.17
+	Hs
		496444 FUS_HUMAN (110-216): 7.15e-11: 67.5: 24.07		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Mm
		498044 EWS_MOUSE (126-217): 4.96e-16: 84.1: 26.60		TAU_MOUSE (1-758): 1.4e-69: 244: 70.17
+	Hs
		554269 U2AF2_HUMAN (129-356): 2.97e-32: 133: 22.03		MUC1_HUMAN (242-751): 2.66e-25: 114: 10.84
+	Hs
		967173 EWS_HUMAN (126-217): 8.36e-16: 83.3: 26.60		MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57
+	Hs
		726817 FUS_HUMAN (110-216): 7.15e-11: 67.5: 24.07		MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57
+	Hs
		516595 PABP1_HUMAN (62-264): 9.56e-30: 127: 12.14		KMT2C_HUMAN (83-649): 6.28e-09: 61.8: 12.91
+	Hs
		967541 EWS_HUMAN (126-217): 8.36e-16: 83.3: 26.60		PCLO_HUMAN (46-758): 3.43e-16: 85.9: 9.19