HitPredict

Interactor 1: HTSF1 (O43719)
17S U2 SnRNP complex component HTATSF1 (HIV Tat-specific factor 1) (Tat-SF1)
Gene: HTATSF1

Interactor 2: RSMN (P63162)
Small nuclear ribonucleoprotein-associated protein N (snRNP-N) (Sm protein D) (Sm-D) (Sm protein N) (Sm-N) (SmN) (Tissue-specific-splicing protein)
Gene: SNRPN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	28514442, 33961781, 17353931
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005681 - spliceosomal complex GO:0005686 - U2 snRNP
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 755 Hs			1 240
+	Hs
		212101 HTSF1_HUMAN (1-755): 2.64e-92: 306: 100.00		RSMB_HUMAN (1-168): 1.09e-43: 148: 96.43
+	Hs
		123790 HTSF1_HUMAN (1-755): 2.64e-92: 306: 100.00		SPT5H_HUMAN (100-228): 4.97e-25: 105: 17.69
+	Mm
		646096 TIA1_MOUSE (127-376): 1.76e-31: 129: 15.75		RSMB_MOUSE (1-168): 3.04e-45: 152: 96.43
+	Hs
		538976 ELAV1_HUMAN (133-381): 1.21e-29: 122: 15.69		RSMB_HUMAN (1-168): 1.09e-43: 148: 96.43
+	Sc
		376799 PABP_YEAST (62-422): 9.79e-26: 114: 13.46		RSMB_YEAST (1-165): 2.64e-36: 128: 28.72
+	Hs
		538912 EWS_HUMAN (126-217): 8.36e-16: 83.3: 26.60		RSMB_HUMAN (1-168): 1.09e-43: 148: 96.43
+	Hs
		538850 FUS_HUMAN (110-216): 7.15e-11: 67.5: 24.07		RSMB_HUMAN (1-168): 1.09e-43: 148: 96.43
+	Hs
		123866 FUS_HUMAN (110-216): 7.15e-11: 67.5: 24.07		SPT5H_HUMAN (100-228): 4.97e-25: 105: 17.69
+	Hs
		297856 EWS_HUMAN (126-217): 8.36e-16: 83.3: 26.60		SC24D_HUMAN (124-240): 5.64e-18: 84.7: 21.95
+	Hs
		967541 EWS_HUMAN (126-217): 8.36e-16: 83.3: 26.60		PCLO_HUMAN (49-237): 3.05e-09: 58.9: 13.61