HitPredict

Interactor 1: HTSF1 (O43719)
17S U2 SnRNP complex component HTATSF1 (HIV Tat-specific factor 1) (Tat-SF1)
Gene: HTATSF1

Interactor 2: SRSF4 (Q08170)
Serine/arginine-rich splicing factor 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB) (Splicing factor, arginine/serine-rich 4)
Gene: SRSF4

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	1.00	0.656

Property	Details
Experiments	22365833
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 755 Hs			1 494
+	Hs
		474020 PAB4L_HUMAN (116-346): 2.02e-51: 185: 20.17		SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50
+	Hs
		992875 PABP5_HUMAN (118-346): 2.01e-38: 148: 19.83		SRSF1_HUMAN (3-166): 2.36e-57: 192: 41.42
+	Hs
		992743 ELAV2_HUMAN (117-424): 7.45e-35: 138: 13.06		SRSF1_HUMAN (3-166): 2.36e-57: 192: 41.42
+	Hs
		1028593 PABP5_HUMAN (118-346): 2.01e-38: 148: 19.83		SRSF9_HUMAN (3-216): 2.36e-52: 178: 36.53
+	Hs
		641736 U2AF2_HUMAN (129-356): 2.97e-32: 133: 22.03		SRSF1_HUMAN (3-166): 2.36e-57: 192: 41.42
+	Hs
		1020247 ELAV2_HUMAN (117-424): 7.45e-35: 138: 13.06		SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50
+	Hs
		641754 U2AF2_HUMAN (129-356): 2.97e-32: 133: 22.03		SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50
+	Hs
		641753 U2AF2_HUMAN (129-356): 2.97e-32: 133: 22.03		SRSF9_HUMAN (3-216): 2.36e-52: 178: 36.53
+	Hs
		641738 U2AF2_HUMAN (129-356): 2.97e-32: 133: 22.03		SRSF4_HUMAN (1-468): 4.56e-48: 174: 100.00
+	Cn
		111495 J9VUR9_CRYNH (85-374): 1.13e-35: 145: 19.60		J9VJ75_CRYNH (3-179): 9.05e-43: 161: 30.85
+	Hs
		1119141 PABP5_HUMAN (118-346): 2.01e-38: 148: 19.83		PAP1L_HUMAN (1-189): 2.51e-32: 132: 16.50
+	Hs
		516635 PABP5_HUMAN (118-346): 2.01e-38: 148: 19.83		PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50
+	Hs
		516484 ELAV2_HUMAN (117-424): 7.45e-35: 138: 13.06		PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50
+	Hs
		516364 U2AF2_HUMAN (129-356): 2.97e-32: 133: 22.03		PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50
+	Hs
		474021 PAB4L_HUMAN (116-346): 2.02e-51: 185: 20.17		PABP4_HUMAN (100-185): 3.19e-11: 67.7: 19.78
+	Hs
		474034 PABP5_HUMAN (118-346): 2.01e-38: 148: 19.83		PAB4L_HUMAN (100-185): 1.44e-10: 65: 19.78
+	Hs
		1020249 ELAV2_HUMAN (117-424): 7.45e-35: 138: 13.06		PABP4_HUMAN (100-185): 3.19e-11: 67.7: 19.78
+	Hs
		474019 ELAV2_HUMAN (117-424): 7.45e-35: 138: 13.06		PAB4L_HUMAN (100-185): 1.44e-10: 65: 19.78
+	Hs
		641756 U2AF2_HUMAN (129-356): 2.97e-32: 133: 22.03		PABP4_HUMAN (100-185): 3.19e-11: 67.7: 19.78