Interactor 1: CIKS (O43734)
E3 ubiquitin ligase TRAF3IP2 (EC 2.3.2.27) (Adapter protein CIKS) (Connection to IKK and SAPK/JNK) (E3 ubiquitin-protein ligase CIKS) (Nuclear factor NF-kappa-B activator 1) (ACT1) (TRAF3-interacting protein 2)
Gene: TRAF3IP2

Interactor 2: I17RC (Q8NAC3)
Interleukin-17 receptor C (IL-17 receptor C) (IL-17RC) (Interleukin-17 receptor homolog) (IL17Rhom) (Interleukin-17 receptor-like protein) (IL-17RL) (ZcytoR14)
Gene: IL17RC

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 24120361
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains SEFIR~SEFIR
Common GO terms GO:0005102 - signaling receptor binding
GO:0006954 - inflammatory response
GO:0038173 - interleukin-17A-mediated signaling pathway
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 574
Hs

1 791
+ Mm
+ Hs
+ Mm
+ Hs

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Last updated: 15 Jul 2024