HitPredict

Interactor 1: ITM2A (O43736)
Integral membrane protein 2A (Protein E25)
Gene: ITM2A

Interactor 2: ATP7A (Q04656)
Copper-transporting ATPase 1 (EC 7.2.2.8) (Copper pump 1) (Menkes disease-associated protein)
Gene: ATP7A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005794 - Golgi apparatus GO:0005886 - plasma membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 263 Hs			1 1500
+	Rn
		416154 ITM2B_RAT (1-261): 5.33e-142: 400: 40.45		AT1A1_RAT (720-1472): 0: 579: 14.95
+	Rn
		416173 ITM2B_RAT (1-261): 5.33e-142: 400: 40.45		AT1A3_RAT (720-1465): 0: 574: 15.19
+	Hs
		531005 ITM2B_HUMAN (1-261): 3.52e-138: 390: 40.08		AT1A3_HUMAN (720-1465): 0: 575: 15.19
+	Rn
		416165 ITM2B_RAT (1-261): 5.33e-142: 400: 40.45		AT1A2_RAT (720-1465): 3.15e-179: 564: 15.79
+	Rn
		1140241 ITM2B_RAT (1-261): 5.33e-142: 400: 40.45		AT2A1_RAT (729-1431): 5.34e-165: 525: 17.73
+	Hs
		164040 ITM2B_HUMAN (1-261): 3.52e-138: 390: 40.08		AT2A1_HUMAN (729-1431): 1.69e-165: 527: 18.09
+	Hs
		212283 ITM2A_HUMAN (1-263): 1.34e-142: 402: 100.00		ATP7B_HUMAN (1-571): 2.75e-100: 355: 26.26