HitPredict

Interactor 1: AP1G1 (O43747)
AP-1 complex subunit gamma-1 (Adaptor protein complex AP-1 subunit gamma-1) (Adaptor-related protein complex 1 subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain) (Gamma1-adaptin) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1)
Gene: AP1G1

Interactor 2: PP6R2 (O75170)
Serine/threonine-protein phosphatase 6 regulatory subunit 2 (SAPS domain family member 2)
Gene: PPP6R2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 822 Hs			1 966
+	Hs
		257152 AP2A1_HUMAN (3-808): 0: 594: 24.39		PP6R2_HUMAN (1-966): 0: 893: 100.00
+	Hs
		257172 AP2B1_HUMAN (30-800): 0: 552: 16.59		PP6R2_HUMAN (1-966): 0: 893: 100.00
+	Hs
		257175 AP1B1_HUMAN (30-800): 0: 547: 17.36		PP6R2_HUMAN (1-966): 0: 893: 100.00
+	Hs
		321563 AP2A1_HUMAN (3-808): 0: 594: 24.39		PP6R3_HUMAN (1-914): 0: 746: 46.31
+	Hs
		302165 AP2A2_HUMAN (3-813): 0: 582: 24.55		PP6R3_HUMAN (1-914): 0: 746: 46.31
+	Hs
		925891 AP2B1_HUMAN (30-800): 0: 552: 16.59		PP6R3_HUMAN (1-914): 0: 746: 46.31
+	Hs
		1014025 AP1B1_HUMAN (30-800): 0: 547: 17.36		PP6R3_HUMAN (1-914): 0: 746: 46.31
+	Hs
		926056 AP2B1_HUMAN (30-800): 0: 552: 16.59		PP6R1_HUMAN (1-898): 0: 640: 39.94
+	Hs
		203194 AP2A1_HUMAN (3-808): 0: 594: 24.39		SYNJ1_HUMAN (399-965): 5.49e-29: 127: 10.15
+	Rn
		1144064 Q66HM2_RAT (3-808): 0: 584: 24.67		SYNJ1_RAT (399-965): 1.33e-30: 132: 11.27
+	Hs
		203219 AP2B1_HUMAN (30-800): 0: 552: 16.59		SYNJ1_HUMAN (399-965): 5.49e-29: 127: 10.15
+	Hs
		203223 AP1B1_HUMAN (30-800): 0: 547: 17.36		SYNJ1_HUMAN (399-965): 5.49e-29: 127: 10.15
+	Sc
		777331 AP3D_YEAST (6-666): 1.86e-111: 364: 20.17		SA185_YEAST (365-717): 5.56e-41: 165: 14.25