HitPredict

Interactor 1: AP1G1 (O43747)
AP-1 complex subunit gamma-1 (Adaptor protein complex AP-1 subunit gamma-1) (Adaptor-related protein complex 1 subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain) (Gamma1-adaptin) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1)
Gene: AP1G1

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 822 Hs			1 758
+	Hs
		321471 AP2A1_HUMAN (3-808): 0: 594: 24.39		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		302095 AP2A2_HUMAN (3-813): 0: 582: 24.55		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496790 AP2B1_HUMAN (30-800): 0: 552: 16.59		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496926 AP1B1_HUMAN (30-800): 0: 547: 17.36		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Rn
		577190 AP2A2_RAT (3-808): 0: 585: 24.82		TAU_RAT (1-758): 4.86e-75: 260: 71.47
+	Rn
		94239 Q66HM2_RAT (3-808): 0: 584: 24.67		F1LST4_RAT (1-757): 8.59e-75: 260: 71.56
+	Hs
		150164 AP3D1_HUMAN (7-712): 6.12e-177: 542: 21.24		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Mm
		497920 AP2A1_MOUSE (3-808): 0: 595: 25.00		TAU_MOUSE (1-758): 1.4e-69: 244: 70.17
+	Rn
		581970 AP2B1_RAT (30-800): 0: 552: 16.59		TAU_RAT (1-758): 4.86e-75: 260: 71.47
+	Rn
		94193 AP2B1_RAT (30-800): 0: 552: 16.59		F1LST4_RAT (1-757): 8.59e-75: 260: 71.56
+	Mm
		498136 AP2B1_MOUSE (30-800): 0: 552: 16.59		TAU_MOUSE (1-758): 1.4e-69: 244: 70.17
+	Rn
		1144064 Q66HM2_RAT (3-808): 0: 584: 24.67		SYNJ1_RAT (72-557): 4.95e-13: 75: 12.10
+	Hs
		203194 AP2A1_HUMAN (3-808): 0: 594: 24.39		SYNJ1_HUMAN (7-411): 1.53e-09: 63.9: 9.76
+	Hs
		926047 AP2B1_HUMAN (30-800): 0: 552: 16.59		MAGL2_HUMAN (1-739): 1.99e-19: 95.9: 10.23
+	Hs
		203219 AP2B1_HUMAN (30-800): 0: 552: 16.59		SYNJ1_HUMAN (7-411): 1.53e-09: 63.9: 9.76
+	Hs
		203223 AP1B1_HUMAN (30-800): 0: 547: 17.36		SYNJ1_HUMAN (7-411): 1.53e-09: 63.9: 9.76